Regulatory T cells (Treg) are essential for immune balance, preventing overreactive responses and autoimmunity.Although traditionally characterized as CD4+CD25+CD127lowFoxP3hi, recent research has revealed diverse Treg subsets such as Tr1, Tr1-like, and CD8 Treg.Treg dysfunction leads to severe autoimmune diseases and immune-mediated inflammatory d
Background: Pulmonary hypertension (PH) is a debilitating condition characterized by elevated pulmonary arterial pressure and progressive vascular remodelling, leading to exercise intolerance.The progression of PAH is regulated at a cellular and molecular the official playboy bunny gold rabbit head zippo lighter level which influences various physi
This paper proposes a novel efficient inspired algorithm based on snow avalanches in nature which is named the Snow Avalanches Algorithm (SAA), for solving the benchmark and engineering optimization problems and determining the global solution.The proposed algorithm is modeled using four phases including avalanche due to mountain slope, human facto